What is the normal serum alanine aminotransferase (ALT) value for Thai subjects with the low risk of liver diseases?

Background It still remains unclear whether the currently used normal range for serum alanine aminotransferase (ALT) levels really reflects a healthy liver. Objective To determine the thresholds for healthy ALT values or the normal value for Thai subjects with the low risk of liver diseases who participate in the annual physical checkup at King Chulalongkorn Memorial Hospital (KCMH). Materials and Methods We retrospectively reviewed the medical records of annual health examination, including questionnaires conducted at KCMH, Thailand from January to December 2006. A group of the low risk of liver diseases was selected by excluding patients who showed any abnormalities of the risk factors that were significantly associated with the serum ALT level, including hepatitis B, hepatitis C, alcohol consumption, diabetes, hyperlipidemia and obesity. นพินธต์น้ฉบบั